In the dynamic field of biotechnology manufacturing, Single-Use-System (SUS) Bioreactors have become an integral part of many bioprocess facilities for bioproducts. SUSs are comparatively safer, simpler and more flexible than their stainless-steel bioreactor counterpart, and for that reason, their usage is commonly used in the biopharmaceutical industry for complex projects such as the development and production of new vaccines, therapies and diagnostic equipment.
Traditional bioreactors, designed primarily for mammalian cell culture, often fall short in addressing the specific needs of microbial cultures, such as elevated oxygen transfer capacity and precise temperature control. Identifying this gap, TECNIC proudly introduces the ePROD SU, a scalable Dual-Purpose Bioreactor/Fermenter SU Bioreactor for both cellular and microbial cultures.
Engineered to scale seamlessly from 300L to 1000L, both cellular and microbial versions of ePROD® SU offer one indisputable operational productive advantage over stainless steel bioreactors; as Single-Use Systems (SUSs) eliminate the necessity for CIP/SIP and cleaning validation, they reduce downtime between batches, saves production time, and simultaneously ensures a lower risk of cross-contamination. In turn, this fast and flexible manufacture characteristic accelerates commercialization of biopharmaceutical products,
Demonstrating TECNIC’s unwavering commitment to innovation, the SU industrial bioreactor signifies a promising future for biomanufacturing. This equipment, engineered for superior performance and user convenience, showcases precision temperature control, efficient agitation, and comprehensive instrumentation. It also delivers unparalleled performance and operational ease in both microbial and cellular bioprocesses. Equipped with a robust automation system and an optimized single-use bioreactor bag assembly, the ePROD SU STR ensures operational simplicity.
Complementing this equipment, TECNIC eBAG® 3D STR, designed and manufactured in our ISO7 Clean Room facilities, presents an innovative solution catering to both microbial and cell culture applications. It effectively addresses the most demanding challenges in the market.
Elevating biopharmaceutical production with scalable single-use industrial bioreactors for vaccine and therapy development
Designed to accommodate both cellular and microbial eBAG® 3D STR, the TECNIC ePROD® SU Bioreactor features a modular stainless-steel vessel with advanced capabilities. It incorporates an efficient dimpled jacket for precise heat transfer, ensuring optimal cooling and heating. At the same time, the system boasts a high-performance bottom-mounted, magnetically coupled drive for impeccable agitation, while the incorporated load cells provide accurate weight measurement. Finally, comprehensive process instrumentation is a hallmark of this bioreactor, including mass flow controllers, peristaltic pumps, and probe transmitters. Overall, this modular design ensures adaptability and efficiency for diverse bioprocessing needs.
Featuring a 15-inch touch screen interface, the SU industrial bioreactor offers an intuitive control system for monitoring and adjusting key parameters in culture growth, ensuring maximum accuracy in the process.
Equipped with a set of different sensors (single-use or re-usable) that control and monitor pH, pO2, temperature, and level/foam in real time, it allows the precise control over culture conditions for cell and microorganism growth.
Available in various sizes (300L and 1000L), TECNIC’s SU industrial bioreactor offers versatile volumes to meet specific needs.
Uncompromising performance and convenience
Two general configurations are available, catering to different applications. The microbial configuration comes with Rushton impellers, while the cellular configuration features pitch blade SU impellers. Standard configurations offer flexibility in terms of the number, locations, and types of ports, including those for additional solutions, stirring agitation, exhaust connection, overlay gas entrance in the top area along with sensors port, and liquid transfer or sampling ports at the bottom area. Moreover, in some cases, we can adapt it to your needs and add all the accessories necessary to meet the most challenging demands of the market. Elevate your operational efficiency by embracing the versatility offered through these diverse configuration choices.
Optimized agitation system
Two precision-controlled single-use impellers (6-blade Rushton turbine for microbial fermentation and 3-pitched blade for cell culture) governed by a precise motor ensure maximum
efficiency and productivity.
The eBAG® 3D STR eliminates higher costs associated with cleaning, validation, and maintenance, providing a cost-effective alternative for bioprocess fermentations.
Manufactured in ISO 7 cleanroom facilities, eBAG® 3D STR ensure the highest quality, integrity, and safety of stored products. Various certifications are offered, ensuring compliance with industry standards, and thorough leak tests can be conducted for enhanced reliability.
