High-Performance Non-Invasive Flow Monitoring for Sterile Manufacturing
At Fluid Biosolutions, we specialise in providing advanced instrumentation that supports the manufacture of sterile pharmaceutical products. One of our flagship offerings is the SONOFLOW® CO.55 Clamp-On Ultrasonic Flow Meter – a non-contact, highly accurate flow measurement solution designed for flexible tubing systems in the biopharmaceutical and life sciences industries.
If you’re seeking an ultrasonic flow meter that delivers precision, sterility, and scalability across all stages of drug manufacturing, the SONOFLOW CO.55 is the ideal choice.
An ultrasonic flow meter is a device that calculates flow rate using the transit-time principle. By sending and receiving ultrasonic waves through the wall of a tube, the device measures how long the wave takes to travel with and against the flow. The time difference reveals the velocity of the liquid, which is then used to calculate the total flow volume.
Unlike traditional flow meters, clamp-on ultrasonic flow meters are entirely non-invasive. They don’t require fluid contact, eliminating contamination risk and simplifying validation in GMP-regulated environments.
The SONOFLOW CO.55 was purpose-built for non-contact flow measurement in flexible tubing. As a clamp-on ultrasonic flow meter, it’s particularly well-suited for single-use bioprocessing, fill-finish operations, and drug development applications.
Its versatility across upstream and downstream processing makes it a staple for facilities that require precise, real-time flow data without disrupting the system.
The sensor clamps directly onto flexible tubing, eliminating contact with the process fluid and reducing contamination risk. Ideal for cleanrooms, sterile environments, and validated production processes.
Delivers real-time measurement accuracy of up to ±1% under ideal conditions (typically ±2%), with a repeatability of 1.5%. This high-performance level supports regulatory compliance and quality assurance in precise bioprocessing environments.
With integrated electronics, RS-485 Modbus connectivity, and no external transmitter required, this ultrasonic flow sensor is easy to install in existing systems.
The sensor is durable and can be cleaned and reused across multiple process runs, offering both sustainability and reduced cost per batch.
Compatible with tubing sizes from 0.125″ to 1.375″ outer diameter, with multiple housing options in aluminium or stainless steel.
With SONOTEC’s optional Monitor software, users can configure sensor settings, monitor data in real time, perform calibration, and log measurement values on-site.
| Parameter | Value |
|---|---|
| Flow Range | 10 mL/min – 200 L/min |
| Accuracy | ±1% (ideal conditions), typically ±2% |
| Repeatability | 1.5% |
| Tubing OD Range | 0.125″ – 1.375″ |
| Operating Temperature | 0°C – 60°C |
| Voltage | 12–30 VDC |
| Outputs | 4–20 mA, RS-485 Modbus, Frequency (0–20 kHz), Digital Input |
| Material Options | Aluminium or Stainless Steel Housing |
View full specifications in the technical documentation.
The SONOFLOW CO.55 plays a critical role across all key production steps:
With accurate flow monitoring during both upstream and downstream processes, this ultrasonic flow sensor helps ensure consistent yields, optimal dosing, and enhanced product integrity.
Thanks to its compact footprint and intuitive connectivity, the SONOFLOW CO.55 is easy to retrofit into existing systems without interrupting the process.
Optional accessories include:
Fluid Biosolutions is your trusted Australian supplier of advanced bioprocess equipment. We go beyond product delivery—we provide complete support, from selection and integration to post-sale service.
Yes, the clamp-on design allows for hygienic reuse on disposable tubing, aligning with modern single-use manufacturing workflows.
Yes. The SONOFLOW CO.55 works seamlessly with most flexible plastic tubing materials commonly used in biopharma production.
While multiple tubing sizes are supported, sensors are optimised for specific outer diameters. Speak with our team to match the correct sensor for your process.
Absolutely. With non-contact measurement, real-time accuracy, and reusable housing, it aligns with GMP expectations for sterility, traceability, and performance validation.
Looking for a reliable ultrasonic flow meter that delivers precise, contamination-free monitoring for your sterile manufacturing processes?
Contact Fluid Biosolutions today for pricing, product demonstrations, or technical support.
The non-invasive measurement of flow rates in fluid-filled tubing is essential across a wide range of scientific, industrial and regulated environments. SONOTEC’s ultrasonic flow sensors are relied upon globally in bioprocessing, pharmaceutical manufacturing, medical science, automation technology, mechanical engineering and hydraulic system design, where precise, contamination-free monitoring is critical.
SONOTEC’s SONOFLOW® sensor series is engineered to deliver fast, accurate and repeatable flow measurement in flexible tubing systems. Because these ultrasonic sensors operate using a clamp-on, non-contact design, the process fluid never interacts with the device, making the technology ideal for applications with strict hygiene, GMP compliance and sterility expectations.
Designed for single-use bioprocessing, sterile manufacturing, cleanroom operations and high-precision R&D environments, SONOFLOW sensors enable real-time flow monitoring without interrupting production or compromising product integrity.
Beyond their standard product line, SONOTEC also designs and manufactures customised ultrasonic sensors for specialised applications. Their engineering team can tailor both the physical sensor design and the internal evaluation algorithms to meet unique industry requirements—including niche tubing geometries, specialised fluids, extreme environmental conditions or proprietary system configurations.
This flexibility makes SONOTEC a preferred technology partner for OEMs, integrators and manufacturers looking to embed ultrasonic flow measurement into advanced equipment, automation systems or complex bioprocessing platforms.
Efficient, accurate fluid control and real-time monitoring are vital in modern biopharmaceutical manufacturing. At Fluid Biosolutions, we deliver advanced pumps & sensors engineered for sterile, single-use systems and GMP-regulated environments. Whether you’re managing media and buffer preparation, fill-finish operations or closed-loop automation, our solutions provide the precision and reliability your process demands.
A robust bioprocess relies on two foundational elements: the correct delivery of fluids and rigorous monitoring of critical parameters. Pumps ensure controlled movement of liquids – such as media, buffer, reagents or final product – while sensors provide accurate real-time data on flow, temperature, pressure, conductivity and more. Together, they underpin closed-system bioprocessing, minimise contamination risk, and enable consistent yield and quality.
Industries from cell & gene therapy to large-scale fill-finish use these tools to maintain operational integrity, scale effectively and meet regulatory standards.
By properly combining the right pump and matched sensor, you gain improved process control, less manual intervention, and stronger traceability – critical in regulated manufacturing.
Start with your fluid system requirements:
Once you’ve defined these, match your system to a pump rated for your flow/viscosity demands and a sensor calibrated for your fluid and environment. Our team at Fluid Biosolutions can assist you in aligning the right solution to your workflow, scale and compliance needs.
We’re more than a supplier – we’re your Australian partner for advanced bioprocess equipment. When you select us, you benefit from:
Browse our full category of pumps and sensors tailored for bioprocess applications. If you’d like help selecting the right solution for your scale or process, contact our team for expert guidance.
Maintaining a closed, contamination-free fluid path is essential in modern biopharmaceutical and single-use manufacturing. At Fluid Bio Solutions, we supply tube sealers and welders engineered for GMP environments, helping teams create aseptic tube welds and seals that support safe fluid transfers from upstream processing through to final fill and finish.
Our solutions are built for reliability, repeatability and cleanroom efficiency, making them an ideal fit for pharmaceutical manufacturing, biotechnology, cell and gene therapy, and any operation relying on single-use tubing systems.
As bioprocesses shift toward closed, single-use formats, the need for validated sterile connections has never been higher. Tube welders enable sterile, permanent connections between thermoplastic tubing, while tube sealers create strong, leak-free tube closures that maintain aseptic integrity.
These devices minimise manual handling, reduce contamination risk and ensure consistent, traceable results across batches, an essential requirement in regulated environments.
Common applications include:
Our category includes devices designed to meet the expectations of high-performance bioprocessing:
Systems create sterile connections without exposing product to the environment, supporting contamination-free manufacturing.
Ideal for commonly used thermoplastic elastomers (TPE), PVC, EVA and C-Flex® used in single-use tubing systems.
Short cycle times and validated weld strength allow seamless operation in high-throughput cleanrooms.
Low-particulate operation, compact form factors and easy integration with SOP-driven workflows.
Clear prompts, error reduction features and reliable process monitoring support consistent use across teams.
Some systems offer electronic records or audit-supporting output compatible with regulated manufacturing processes.
Every facility’s needs differ based on tubing type, OD/wall thickness, fluid characteristics and production scale. When selecting equipment, consider:
Fluid Bio Solutions provides guidance to help match the correct system to your operational, quality and regulatory needs.
We supply GMP-ready tube sealers and welders supported by local stock, technical expertise and responsive service. Our team assists with product selection, validation considerations and integration into existing bioprocess lines, ensuring you get a solution that enhances sterility, efficiency and process control.
Explore our range today or contact us for tailored recommendations for your facility.
Explore our range of equipment or contact us for a tailored recommendation for your facility.
Bioreactors are at the heart of many bioprocessing and pharmaceutical applications, providing controlled environments for cultivating cells, microorganisms, and biologics. Recent innovations in bioreactor design have transformed these systems, improving efficiency, scalability, and functionality. Here’s an overview of the most impactful advancements, and how they can enhance your processes.
Modern bioreactors integrate several state-of-the-art features, including:
These technologies make it easier to optimise bioprocesses, ensuring maximum yield and efficiency. Fluid Biosolutions offers a range of advanced bioreactor systems that support varied applications, ensuring businesses can meet production goals effectively.
One of the most impactful innovations in recent years is the adoption of single-use bioreactors, which offer:
These single-use systems are perfect for flexibility and scalability, especially in environments where speed and safety are critical.
Achieving high yields requires optimising key elements of bioreactor systems, such as:
At Fluid Biosolutions, our bioreactors are designed to deliver superior performance, ensuring consistent product quality across every batch.
Silicone tubing is an essential component in bioreactors, facilitating the sterile transfer of fluids and gases. Key benefits of silicone tubing include:
Fluid Biosolutions provides high-purity silicone tubing that meets the stringent demands of the bioprocessing industry, ensuring your bioreactor systems remain efficient and safe.
After cultivation, many processes rely on centrifuge machines for separating biological materials. Centrifuges help:
At Fluid Biosolutions, we offer reliable, high-performance centrifuge machines designed to complement bioreactor systems.
The integration of automation into bioreactors has revolutionised control and monitoring. Key benefits include:
Automation helps improve scalability and efficiency, ensuring that businesses can meet the growing demands of the biotech and pharmaceutical sectors.
As environmental sustainability becomes a priority, innovations in bioreactor design are also focusing on:
This trend towards sustainability not only benefits the environment but also reduces operational costs for businesses.
Innovations in bioreactor design are enabling biotech and pharmaceutical companies to produce better-quality products more efficiently. From single-use bioreactors to advanced automation, the latest trends in bioreactor technology offer tremendous potential for improving production processes. Combined with high-purity silicone tubing and centrifuge machines, these innovations help businesses achieve the highest levels of productivity and safety.
At Fluid Biosolutions, we’re dedicated to providing state-of-the-art bioreactor systems that meet the demands of modern biotechnology. Contact us today to optimise your bioprocessing systems.
Unit 4, 5 Enterprise Drive Rowville VIC 3178
Phone: 0455 599 168
Email: sales@fluidbiosolutions.com.au
